Understanding the movement patterns of predators is crucial to defining their role in ecosystems as well as developing effective management and conservation policies. Reef associated sharks are often considered to have similar habitat requirements and movement patterns. Here we examined the long-term presence and movements of several species of reef-associated sharks in the central and southern Great Barrier Reef. Long-term acoustic telemetry data collected from grey reef, blacktip reef, whitetip reef, weasel, silvertip, tiger and bull sharks over a five year period revealed complex movement patterns that vary by size, sex, species and habitat type. Home range and network analyses demonstrated that the amount of space used and location of home ranges varied among species and locations. Despite their similar sizes, grey reef, blacktip reef, whitetip reef and weasel sharks moved and used space differently. These results suggest biological needs may be key drivers of reef shark movement and distribution. The differences observed in reef shark movement patterns are relevant to management of reef shark populations as concerns around these species increase within and beyond the Great Barrier Reef.