Grenadiers are an important commercial and ecosystem component of the demersal and mid water fisheries of Chile and Australia, locally known as Patagonian grenadier (Macruronus magellanicus) and blue grenadier (Macruronus novaezelandiae) respectively. The Chilean spawning area is located in the bifurcation of the Humboldt and Cape Horn currents, influenced by the west wind drift. For Australia, the spawning area is located off the west coast of Tasmania. Bayesian correlations and Bayes Factor Analysis indicate important relationships between the strength of a number of fish stocks and climate indices on both global and regional scales (such as the Interdecadal Pacific Oscillation (IPO), Southern Annular Mode (SAM), the Southern Oscillation Index (SOI), sea surface temperature and wind). Similarly here, recruitment of grenadier stocks on both sides of the Pacific was found to be influenced by regional temperature and wind variables. Negative relationships with SOI were observed for Chilean and Australian populations, and Patagonian grenadier recruitment also showed associations with the time-series of SAM and IPO. Sea surface temperature and wind anomalies presented high correlations with recruitment for both populations. The highest correlations between the global and regional variables were in the summer - autumn period prior to the winter spawning season. It is possible that the global indices are producing a synchronous pattern of recruitment fluctuation for both populations, modified locally by regional variables. We discuss potential biophysical processes that could be responsible for the environment - recruitment correlations.